A 6-month-old baby - okt3

[ArchivalUser]

A 6-month-old baby is brought to the emergency department with a high fever. Physical examination is remarkable only for fever. In the emergency department, the child has a seizure and is admitted to the hospital.
Bacterial culture and Gram stain of blood, CSF, and urine are negative. Intranuclear inclusion bodies are found in the lymphocytes, which are the predominant cell type in the CSF. A few days later, as the fever resolves, multiple small blanchable macules and papules are observed on the infant™s back.
The most likely pathogen is a member of which of the following viral families?

(A) Herpesviridae

(B) Orthomyxoviridae

© Paramyxoviridae

(D) Parvoviridae

(E) Poxviridae

[ArchivalUser]

aa

[ArchivalUser]

A...roseola

[ArchivalUser]

The correct answer is A. Roseola infantum, or exanthem subitum, is the disease associated with human herpesvirus 6 (HHV-6) infection. HHV-6 is a member of Herpesviridae. Symptoms of roseola infantum include high fever followed by a maculopapular rash that resolves uneventfully in a few hours or days. Most children are infected by 2 years of age. Between 80 and 100% of adults are seropositive, and HHV-6 is shed in
their saliva.

Orthomyxoviridae (choice B) is the family of influenza viruses.

Paramyxoviridae (choice C) is the family of parainfluenza viruses, measles, mumps, and respiratory syncytial viruses.

Parvoviridae (choice D) is the family of parvovirus B19

Poxviridae (choice E) is the family of smallpox, monkeypox, vaccinia virus, and molluscum contagiosum.