09-17-2007, 07:12 PM
A 32 year old man has had malaise, a low grade fever, and a 4.5 kg weight loss over the past 3 months, he has unilateral cervical lymphadenopathy. Lab shows
Hb 11g/dl; Hct 33%; mean corpuscular volume 80 um3; reticulocyte count 0.5%
Serum iron 25 ug/dl; total iron binding capacity 150 ug/dl (N=250-460)
Examination of tissue obtained on biopsy of a lymph node shows Hodgkin™s disease, nodular sclerosing type, the most likely cause of the anemia is
a. abnormal utilization of iron
b. extravascular hemolysis
c. folate deficiency
d. iron deficiency
e. marrow aplasia
Hb 11g/dl; Hct 33%; mean corpuscular volume 80 um3; reticulocyte count 0.5%
Serum iron 25 ug/dl; total iron binding capacity 150 ug/dl (N=250-460)
Examination of tissue obtained on biopsy of a lymph node shows Hodgkin™s disease, nodular sclerosing type, the most likely cause of the anemia is
a. abnormal utilization of iron
b. extravascular hemolysis
c. folate deficiency
d. iron deficiency
e. marrow aplasia