11-06-2007, 09:59 AM
A 39-year-old man is having a routine physical examination because of a history of colon cancer in his family. He has no abdominal tenderness or masses, and active bowel sounds are present. However, his stool is positive for occult blood. Colonoscopy is performed. There are 7 polyps found in the ascending colon: three of these are small 0.5 cm pedunculated tubular adenomas, three are 1 cm tubulovillous adenomas, and one is a 2 cm sessile villous adenoma in the cecum containing a focus of well differentiated adenocarcinoma. Which of the following is the most likely diagnosis?
A Peutz-Jeghers syndrome
B Chronic ulcerative colitis
C Hereditary non-polyposis colon carcinoma
D Familial polyposis coli
E Gardner syndrome
A Peutz-Jeghers syndrome
B Chronic ulcerative colitis
C Hereditary non-polyposis colon carcinoma
D Familial polyposis coli
E Gardner syndrome