diabetic ketoacidosis - doctortodd

[ArchivalUser]

why are the complications of diabetic keto acidosis cerebral edema, cardiac arythmias, and heart failure.

[ArchivalUser]

My hypothesis:
DKA usually occurs in Type 1 diabetes. One of insulin's function is to pump K into cells by increasing the Na/K pump. Because of lack of insulin there is hyperkalemia. The increased K in the cell with decrease the efflux--> This will tend to depolarize cells leading to Cardiac arrythmias--> heart failure perhaps. I am not sure about the cerebral edema.

[ArchivalUser]

insulin increases k absorption,so in absence of insulin as in DKA there will be hypokalemia.Hypokalemia causes arrythmias.cerebral edema may be due to increase in osmolarity(due to high blood glucose levels).If im wrong, plz correct me.

[ArchivalUser]

diabetes------>hyperglycemia------>dilutional hyponatremia----------->cerebral edema.

diabetes------>lack of insulin------->ineffective na/k pump------------->hyperkalemia----->arrhythmias....