q24 - kola

[ArchivalUser]

Which one of the following enzymes catalyzes high-energy phosphorylation of substrates during glycolysis?

Options:

1. Pyruvate kinase

2. Phosphoglycerate kinase

3. Triose phosphate isomerase

4. Aldolase

5. Glyceraldehyde-3-phosphate dehydrogenase

[ArchivalUser]

22??

[ArchivalUser]

1111........

[ArchivalUser]

sry both 1 and 2.......

[ArchivalUser]

1 and 2 both are substrate level phosphorylations right?

[ArchivalUser]

2.

[ArchivalUser]

1&2

[ArchivalUser]

The Correct Answer is: Glyceraldehyde-3-phosphate dehydrogenase
Explanation:



High-energy phosphate bonds are added to the substrates of glycolysis at three steps in the pathway. Hexokinase or, in the case of the liver, glucokinase”adds phosphate from ATP to glucose to form glucose-6-phosphate. Strictly speaking, this is not always considered a step of the glycolytic pathway. Phosphofructokinase uses ATP to convert fructose-6-phosphate to fructose-1,6-phosphate. Using NAD+ in an oxidation-reduction reaction, inorganic phosphate is added to glyceraldehyde-3-phosphate by the enzyme glyceraldehyde-3-phosphate dehydrogenase to form 1,3-diphosphoglycerate. The enzymes phosphoglycerate kinase and pyruvate kinase transfer substrate high-energy phosphate groups to ADP to form ATP.

[ArchivalUser]

substrate level phosphorylation,,, and phosphorylation of substrates... wht a question.. thanku

[ArchivalUser]

gud one kola.......didnt read carefully.big mistake.