83 - ebnalfady

[ArchivalUser]

A 70-year-old female is treated with sublingual nitroglycerin for her occasional bouts of angina. Which of the following is involved in the action of nitroglycerin?
A.
-adrenergic activity

B.
Phosphodiesterase activity
C.
Phosphorylation of light chains of myosin
D.
Norepinephrine release
E.
cGMP

[ArchivalUser]

ee

[ArchivalUser]

ee

[ArchivalUser]

eeee

[ArchivalUser]

prodrug of nitric oxide

cysteine required to activate it
depletion of which causes tachyphylaxis

=+guanyl cyclase +cGmp =+phosphatase which dephosphorilates MLC(inactive) NOTE not MLCKinase (which is inactive in phosphorilated form)==muscle relaxes

[ArchivalUser]

CC.........