03-15-2008, 08:14 PM
A 60-year-old man comes to the emergency department with shortness of breath and a left-sided dull chest pain. He has had a low-grade fever for the past 3 days. He was treated recently for pneumonia with antibiotics, but says that he never quite returned to baseline. He has no other medical issues and has no allergies. He denies alcohol abuse or drug use. His temperature is 37.8 C (100.0 F), blood pressure is 120/80 mm Hg, and pulse is 70/min. Examination reveals decreased breath sounds on the left and deceased tactile fremitus. Chest x-ray is consistent with a large left-sided pleural effusion greater than 15 mm. A thoracentesis reveals turbid fluid with a white blood cell count of 70,000, red blood cell count of 20,000, LDH of 500 IU/L, and serum LDH of 600 IU/L (normal 50-150 IU/L). A repeat chest x-ray reveals pneumonia in the right upper lobe. Gram stain of the fluid obtained reveals multiple gram-positive diplococci. Pleural fluid pH is 7.1. Which of the following is the most appropriate initial management?
A. Antibiotic coverage and observation
B. Chest tube insertion
C. Diuresis
D. Pleural biopsy
E. Pleurodesis
A. Antibiotic coverage and observation
B. Chest tube insertion
C. Diuresis
D. Pleural biopsy
E. Pleurodesis