q5 - lynna

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A 19-year-old college student presents to the student health center complaining of sore throat and headache. She reports that she had been feeling tired and worn-down for the past few weeks, but attributed it to her busy schedule at school. She denies feeling sad or depressed. On physical exam, she has enlarged posterior chain neck lymph nodes. A peripheral blood smear is looked at by the physician. What histology is likely to be seen on the peripheral blood smear?

A. Knobs on RBC membranes and intrerythrocyte organisms
B. Microspherocytes
C. Normal peripheral blood smear
D. All stages of granulocyte maturation
E. Atypical lymphocytes with clumped chromatin and irregular nuclei surrounded by normal RBCs

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????

[ArchivalUser]

Ans E . Infec. Mononucleosus

[ArchivalUser]

is it E?

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[ArchivalUser]

Corect Answer :E

This patient has a classic presentation for mononucleosis secondary to infection with EBV. The finding on peripheral blood smear is atypical lymphocytes with clumped chromatin and irregular nuclei.


Knobs on RBC membrane and intraerythrocyte organisms is a finding on a peripheral blood smear in a patient with Malaria.

Microspherocytes are a classic finding on a peripheral blood smear in a patient with hereditary spherocytosis.

It is unlikely that this patient would have a completely normal peripheral blood smear.

A patient with Chronic Myelogenous Leukemia would have a peripheral blood smear that demonstrated all stages of granulocyte maturation. It is unlikely that this patient has CML since the mean age of onset is 50 years old and it is slightly more common in men