histo Q for all by imam - lynna

[ArchivalUser]

histo Q for all
#292510
imam

A medical internee of molecular biology is obesrving different stages of phagocytoses of bacteria by macrophases thru the amoeboid movements, formation of psedopodia, endocytoses...
he is enthusiastically used one drug and the all these movements r inhibited resulting the macrophage motionless.
the drug acts on???

A. Microtubules
B.microfilaments
C.intermediate filaments
D.mitochondria
E.Polysomes
F.Tubulin
G.Lysosomes

Imam what's the answer?

Colchicine binds to microtubular protein ( tubulin) involved in cell motility preventing migration of granulocytes and phagocytosis.

[ArchivalUser]

lynna

ans is microfilaments

2 functions
LOCAL MOVement; DIAPEDISIS, AMOEBOID MOVEMENT, PHAGOCYTOSIS, ENDOCYTOSIS
SLIDING movemeNT: ACtIn sliding on mYosin causing contraction

Microtubules are for transport .
in neurons: Kinesisn asso with microtubules for ANTEROGRADE movementand Dyenin for Retrograde movement.
in cilia ;for motion of cilia . and thru cilia ENTIRE ORGANISM MOves.

[ArchivalUser]

The drug is CYTOCHALASIN B
an actin binding drug