Pharm Ques 2 - pepsi00

[ArchivalUser]

A 78 year old woman with type 2 diabetes,diabetic
nephropathy,and hyperuricemia presents to her physician. Physical examination is remarkable for hypertension.Her blood pressure was also elevated on two prior visits. Which ofd the following drugs would be best for initial tx of the woman's ht?

A. Atenolol
B. Captopril
C. Hydrochlorothiazide
D. Indapamide
E.Minoxidil

Explain

Thanks

[ArchivalUser]

B.

[ArchivalUser]

captopril-how does that help, if there is a kidney problem
captopril decreases GFR. Wouldnt it worsen the problem?

[ArchivalUser]

bb

[ArchivalUser]

B is right ans. in diabetic nephropathy ACE inhibitor is good. ACE inhibitor should be avoided only in Renal artery stenosis.

hydrocholorothiazide is lil help ful in hyperurecemia. but in diabetic its not a good choice untill there is vol overload.

[ArchivalUser]

ACE inhibitors decreses intra glomerular pressure thus prevents progression of renal injury in DM .....Captopril