febrile neutropenia please! - pubmed

[ArchivalUser]

Can anyone please post consolidated info on febrile neutropenia...

Thank you in advance

[ArchivalUser]

any ( kind, benevolent, magnanimous, god loving, human philic, lovo philic ..I'm searching for more adjectives in the thesaurus) one please....

thanx for bearing me

[ArchivalUser]

Febrile neutropenia is the development of fever, often with other signs of infection, in a patient with neutropenia, an abnormally low number of neutrophils. Fever is actually caused by infection in 50% of cases, and bacteremia may be present in as many as 20% of all patients.
Febrile neutropenia can develop in any form of neutropenia, but is most generally recognized as a complication of chemotherapy when this is myelosuppressive. Generally, patients with febrile neutropenia are treated with empirical antibiotics until the neutrophil count has recovered and the fever has abated; if the neutrophil count does not improve, treatment may need to continue for two weeks or occasionally more. Guidelines issued in 2002 by the Infectious Diseases Society of America recommend the use of particular combinations of antibiotics in specific settings; mild low-risk cases may be treated with a combination of oral co-amoxiclav and ciprofloxacin, while more severe cases require cefalosporins with activity against Pseudomonas aeruginosa (e.g. ceftazidime), or carbapenems (imipenem or meropenem). A subsequent meta-analysis published in 2006 found that cefepime was associated with more negative outcomes, and that carbapenems (while causing a higher rate of pseudomembranous colitis were the most straightforward in use.