triglyceridemia - woodywoodpecker

[ArchivalUser]

You are managing a patient with the metabolic syndrome.
She is an obese woman with poorly controlled diabetes
and dyslipidemia. Her HbA1C is 8.8% and fasting
plasma glucose is 195 mg/dL. Low-density lipoprotein
(LDL) cholesterol is 98 mg/dL and triglycerides are 276
mg/dL. Her medications include insulin, atorvastatin, hydrochlorothiazide,
and aspirin. What is the best option for
a medication to treat this patient™s hypertriglyceridemia?
A. Cholestyramine
B. Colestipol
C. Ezetimibe
D. Fenofibrate
E. Nicotinic acid

[ArchivalUser]

dd?

but pt is already on statin,watch for myopathy

[ArchivalUser]

well fibrates are the drugs of choice for hypertriglycredimia. Agree wiht Junaid

[ArchivalUser]

ddd

[ArchivalUser]

d?
A and B have intensity to increase TG.
Niacin contraindicated in DM and Gout

[ArchivalUser]

is this a tricky one?
fibrates

[ArchivalUser]

DDD

[ArchivalUser]

ddddddd

[ArchivalUser]

The answer is D. According to the NCEP:ATP III guidelines, treating the
dyslipidemia of the metabolic syndrome should first be directed towards LDL cholesterol
goals (usually 200 mg/dL. The effects of ezetimibe on hypertriglyceridemia are not well
established. Nicotinic acid is effective for treating hypertriglyceridemia but may worsen
glucose control and therefore should be used cautiously in patients with the metabolic
syndrome. Gemfibrozil is more likely to worsen statin myopathy than fenofibrate.