02-04-2009, 05:07 PM
a 23 yo women has skin blisters that results in point mutation in a single gene. epidermal cells in these pts become fragile and rupture.which of the following is the most likely effect of genetic mutation.
1. defective transport of vesicles from the centrimores to the cell membrane
2.disruptive assembly of keratin into intermediate filaments
3 lack of GTP required to form polymeres of tubulin
4.phosphorylation of actin monomers to promote polymerization.
is this phemphigus
1. defective transport of vesicles from the centrimores to the cell membrane
2.disruptive assembly of keratin into intermediate filaments
3 lack of GTP required to form polymeres of tubulin
4.phosphorylation of actin monomers to promote polymerization.
is this phemphigus