nbme4,1 - sherly

[ArchivalUser]

35yo women comes to physician bc of intermittent tingling and numbness of her feel during the past 6 months. has a 30y h/o DM. sensation of joint position is decreased in toes and ankle and vibraion sense is decreased in feet. decreased ankle jerk reflex. pathologcial changes in which of the following:
1. dorsal root ganglion
2. large diameter axon of the distal portion of peripheral nerves
3. motor neurons of the lumbosacral spinal cord
4.spinocerebellar tract of spinal cord
5. STT neurons of dorsal horn

[ArchivalUser]

Ans is 2

[ArchivalUser]

Answer A. Dorsal columns of the spinal cord

[ArchivalUser]

I go for 2 ..Being away from the cell body makes the distal portion of the axon the most liable for injury metabolic diseases .Proximal parts can regenerate better .

[ArchivalUser]

why a?

i thought that with DM larger axons get damaged--meaning ans shld be b.

[ArchivalUser]

i will go with 2