antigenic shift and antigenic drift - usmle_123456

[ArchivalUser]

can anyone explain plz..

[ArchivalUser]

antigenic shift is due to gene recombination
there is sudden drastic change in the antigenic pattern of HA and NA
no similarity to previous virus
leads to pandemics
eg avian influenza

antigenic drift is due to mutation
gradual change
cross reactivity is present
leads to epidemics mainly

[ArchivalUser]

thanx usmlestep19