07-22-2005, 07:05 PM
A 26-year-old woman comes for follow-up in your clinic. During the prior week she was referred by you for a colonoscopy secondary to intermittent bloody diarrhea, tenesmus, and rectal urgency. She is able to eat normally and has not lost weight. She has noted two to three stools per day. Her colonoscopy results reveal mild colonic inflammation and friability involving the distal 30 cm of colon and rectum. Biopsy results are consistent with ulcerative colitis. Her laboratory studies, including blood counts and erythrocyte sedimentation rate, are within the normal range. Which of the following is the most appropriate initial management?
A. Azathioprine
B. Corticosteroid enema
C. Oral aminosalicylate
D. Pulse steroid followed by oral taper
E. Aminosalicylate enema
A. Azathioprine
B. Corticosteroid enema
C. Oral aminosalicylate
D. Pulse steroid followed by oral taper
E. Aminosalicylate enema