Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
Hay guys no body there?
Cris or simonsez where are you?
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
high serum Fe, normal TIBC, normal to high ferritin
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
hi lsa,
how are u doing???
here is what I follow for sideroblastic anemia(i read goljan which I BELIEVE IS THE BEST SOURCE FOR HEMATOLOGY)
MCV:LOW
s erum Fe:high
TIBC: low
% sat: high
serum ferritin:high
rdw:normal
rbc count:low
rbc fep:high(pb poisoning)
hb electrophoresis:normal
marrow iron: increased
tHE PATHOGENESIS INVLOVES decreases Hb synthesis and cytoplasmic maturation defect, the Fe is not being used and thus increased with the resulting parameter changes. If u want the info to come from a more authentic source look it up in Robbins pathology.
chill
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
So you see kaplans are right ...safe to follow them.
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
Baseline is that once Fe saturation is high,TIBC must be low or at the worst near-normal.TIBC indicates what % of ferritin is available for Fe binding;so cannot be high when Fe is high.
Posts: 3,675,934
Threads: 734,342
Joined:
Sep 2021
Reputation:
5
hi,
TIBC is the opposite of serum ferritin, not serum iron.
e.g. in anemia of chronid disease, serum iron is low and TIBC is low as well..
you need to remember about sideroblastic anemia that it is the only anemia with high serum iron becuase it's defect in heme synthesis so there is iron overload.
and serum ferritin is high as well so TIBC is low.
age 196 2004 ed