q...... - usmle_guy

[ArchivalUser]

A 28-year-old woman undergoes allogeneic bone marrow transplantation for acute leukemia. Three weeks later, she has marrow engraftment and her hemoglobin and WBC count are returning to normal. However, she has the appearance of a fine, scaling skin rash over her trunk and upper extremities. These findings are most consistent with which of the following complications?

A Reduced numbers of megakaryocytes

B Keratinocyte apoptosis

C Dry gangrenous necrosis

D Contact dermatitis

E Abrasions from a fight in the ICU

[ArchivalUser]

A..

[ArchivalUser]

purpura ? A

[ArchivalUser]

I suggest B
Graft versus host dis & T cell recognize skin cells as foreign cell & initiate apoptosis of them
See First aid 2010 page 213

[ArchivalUser]

A . b/c of the chemotherapy or radiation before the transparent

[ArchivalUser]

kwt is right....Its apoptosis of keratinocytes........thank u

[ArchivalUser]

nice que ..thnks