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6.what is FIGLU?
7.where does hydroxylation of proline &lysine take place?(inside/outside of fibroblast)
8.where does cross-linking of collagen fibrils take place?(inside/outside of fibroblast)
9.which cofactor is required for cross-linking of collagen?
10.Name 2 bugs which inhibits protein synthesis by ADPribosylation of EF-2.
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7. inside
8. outside
9. vit K
10. Pseudomonas, diphtheria
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figlu test for megaloblastic anemia (i think B12)
and 9 is copper
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6.
7.inside
8.outside
9.Cu
10.pseudomonas and corynebacterium diphtheriae
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6.figlu is formiminoglutamic acid.it is increased in urine in specifically folic acid def.
7.inside.
8.outside
9.lysyle oxidase requires copper.
10.pseudomonas n diphtheria
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Thanks for answering & goodluck!!
ANSWERS:
6.what is FIGLU?
--FIGLU= formiminoglutamic acid. Urinary excretion of formiminoglutamic acid is measured for macrocytic anemias due to deficiency of vit.B12 or folic acid.
7.where does hydroxylation of proline &lysine take place?(inside/outside of fibroblast)
--inside,vit.c is needed.
8.where does cross-linking of collagen fibrils take place?(inside/outside of fibroblast)
--outside
9.which cofactor is required for cross-linking of collagen?
-copper
10.Name 2 bugs which inhibits protein synthesis by ADPribosylation of EF-2.
--Diphtheria & pseudo.aeruginosa.
