02-05-2006, 02:40 AM
1) a synthetic glycoprotein similar to G-CSF is designed .which of teh foll is a characteristic of G-CSF activity that must be taken into account to assure similar biological function?
a) activation of specific cell surface receptor
b0 display of cross - species functionality
c) down regulation of cell growth
d) production by endothelial cells
e( stimulation of megakaryocyte cell production
2)Sum oncogenes are mutanta of normal cell surface receptors that hv tyrosin ekinase activity in their cytoplasmic domains .this type of mutation of such a receptor that is most likely to result in cell transformation in a mutanat protein with which of the foll charac?
a) constitutive activation of cellular trans cription
b) deletion of the cytoplasmic domain
c) failure to become phosphorylated upon receving signal
d) failure to receive the signal that normally activates cell trans cription
e) recognition of different signal than usual
a) activation of specific cell surface receptor
b0 display of cross - species functionality
c) down regulation of cell growth
d) production by endothelial cells
e( stimulation of megakaryocyte cell production
2)Sum oncogenes are mutanta of normal cell surface receptors that hv tyrosin ekinase activity in their cytoplasmic domains .this type of mutation of such a receptor that is most likely to result in cell transformation in a mutanat protein with which of the foll charac?
a) constitutive activation of cellular trans cription
b) deletion of the cytoplasmic domain
c) failure to become phosphorylated upon receving signal
d) failure to receive the signal that normally activates cell trans cription
e) recognition of different signal than usual