Thread Rating:
  • 0 Vote(s) - 0 Average
  • 1
  • 2
  • 3
  • 4
  • 5
nbme 13 q - akm_00
#1
A 43-year-old woman with metastatic colon cancer has maintained remission by taking bevacizumab as a single agent. The ability to administer this agent despite it being a foreign protein is most likely a result of which of the following?

a. The agent being a humanized antibody
b. The agent containing the variable region of a murine antibody molecule directed against vascular endothelial growth factor
c. B-cell dysfunction
d. The immunosuppressive effect of previously administered chemotherapy
e. T-cell dysfunction (wrong)

can anyone plz confirm if its A?
picked C which is wrong. No where in FA is it mentioned if its humanized. Frustrating to get questions wrong because of it.
Reply
#2
Monoclonal antibodies which have "zu" in the word are humanized antibodies .
BevaciZUmab, trastuZUmab etc
Reply
#3
thanks a lot khsaid! you've been of immense help today!
Reply
« Next Oldest | Next Newest »


Forum Jump: