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A 70 yr old man died suddenly and unexpectedly. At autopsy, multiple tissue sites were sampled for microscopic analysis. Examination of the tissues showed noncrystalline amorphous deposits of calcium salts in gastric mucosa, renal interstitium, and alveolar walls of lungs. Which of the following conditions is most likely to explain these findings?
A. Chronic hepatitis
B. Chronic glomerulonephritis
C. Disseminated TB
D. Generalized atherosclerosis
E. Normal aging process
F. Pulmonary emphysema
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distrophic calcification due to Tb, not atherosclerosis cause lungs are a low pressure system and there is no sign of heart failure in the Question stem
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how could you say normal aging process??
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hey carnivor, iam not sure,its my guess,r u sure abt ur answer? all the options other than c and d seem wrong.among these 2 i chose d.
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then why would you say normal aging? TB is the only logical choise, how can you have atheroscleriosis in the lungs with out high pressure in the lungs?
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hey nida,? is the answer? r these nbme questions by chance?
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sorry merlot,right answer plzzzzzzzzzzzzzzz
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B the explanation given is as follows: microscopic findings suggest metastatic calcification, with deposition of calcium salts in tissues that have physiologic mechanisms for losing acid, creating an internal alkaline environment that favors calcium precipitation. chronic renal disease reduces phosphate excretion by the kidney, resulting in an increase in serum phosphate. because the solubility product of calcium and phosphorus must be maintained, the serum calcium is depressed, triggering increased parathyroid hormone output to increase the calcium level, which promotes calcium deposition.
