03-16-2016, 10:03 AM
A 45-year-old woman with no smoking history presents with new onset of cough, shortness of breath, and weight loss. Imaging reveals a peripherally located lung mass with no evidence of primary tumor elsewhere in the body. On light microscopy, the tumoris comprised of poorly formed glands. Which of the following is most likely to be true of this tumor?
(A) Positive for synaptophysin immunostaining
(B) Associated squamous dysplasia at the periphery of the tumor
© Most likely already metastatic, therefore surgery is not recommended
(D) Driven by tobacco-associated carcinogens
(E) Positive for mutation in EGFR
(A) Positive for synaptophysin immunostaining
(B) Associated squamous dysplasia at the periphery of the tumor
© Most likely already metastatic, therefore surgery is not recommended
(D) Driven by tobacco-associated carcinogens
(E) Positive for mutation in EGFR