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Which of the following HLA associations is correctly paired?
a. Chronic active hepatitis- HLA-DR1
b. 21-hydroxylase deficiency- HLA-DR 4
c. Post gonococcal arthritis- HLA-B27
d. Primary Sjogren syndrome- HLA-DR4
e. RA- HLA-DR3
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e???
hla b27 ie reiters is mostly due to chlamydia and is not gonococcal, psoriasis and AS
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You are right. The correct answer is c. The HLA complex is associated with a variety of diseases. Probably the best known association is the one between HLA-B27 and ankylosing spondylitis. HLA-B27 is also associated with postgonococcal arthritis.
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RA is associated with HLA-DR4. Primary Sjogren syndrome is associated with HLA-DR3, 21-Hydroxylase deficiency is associated with HLA-BW47, Chronic active hepatitis is associated with HLA-DR3.
sorry..it would not let me post all the answer...