neuro43 - nishi

[ArchivalUser]

A 30-year-old alcoholic with no apparent liver disease has decided to
abstain from alcohol. Shortly thereafter, he becomes agitated, anxious, has
visual hallucinations, is generally totally disoriented, and suffers bouts of
insomnia. Which of the following agents might be of use in averting these
findings?
a. Primidone
b. Disulfiram
c. Dextroamphetamine
d. Valproic acid
e. Phenylephrine
f. Phenytoin
g. Isoetharine
h. Carbamazepine
i. Amitriptyline
j. Triazolam
k. Diazepam

[ArchivalUser]

b,

[ArchivalUser]

bb

[ArchivalUser]

b....

[ArchivalUser]

BBB

[ArchivalUser]

Ans KKKKKK

Long-acting benzodiazepams
such as diazepam are useful in alcohol withdrawal. Its active metabolite is
eliminated slowly, thereby increasing its duration of action. In patients withliver disease, short-acting agents might prove effective if they are metabolized
to inactive water-soluble metabolites (e.g., oxazepam). Triazolam
would be useful because of its short duration of action.