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pharm-parkinson drug Q - cemmsk
#1
Q:a 72 year old patient with parkinsonism presents with swollen feet. They are red and tender and very painful. You could clear up these symptoms within afew days if you told the patient to stop taking:

a-amantadine
b-benztropine
c-bromocriptine
d-levodopa
e-selegiline
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#2
Amantadinme causes edema and skin mottling
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#3
sorry nrkmani
not the right answer
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#4
i am surprised is not Amantadine.
Is it SElegiline then, cemmsk ?
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#5
ok.
The answer is bromocriptine.

SWOLLEN feet. They are RED and TENDER and VERY PAINFUL.

The presented signs are compatible with ERYTHROMELALGIA, an adverse affect of bromocriptine.

by the way; ERYTHROMELALGIA: (erythros (red), melos (extremities), and algos (pain))

-Episodes often begin with an itching sensation, progressing to a more severe pain with a burning quality. Pain may be so intense that the patient cannot walk; some must even keep their feet immersed in ice water. Most reported cases of secondary erythromelalgia are due to myeloproliferative disorders with thrombocytosis (most commonly polycythemia vera or essential thrombocythemia). side effect of bromocriptine.

amantadine dermatologic side effcet: reddish blue discolored areas of skin, liveo reticularis and also may couse some edema of the extremities.
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#6
(Q was from katzung 's review book.)
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