mx of lithium toxicity - dolly123

[ArchivalUser]

according to mild/moderate/severe toxicity?
Reference to all this was topic on recent Q.
I think for sever tox its hemodilaysi, what about mild and moderate?

anyone please?

[ArchivalUser]

Preliminary studies in animals and humans suggest that sodium polystyrene sulfonate (Kayexalate) is capable of binding lithium and may prevent lithium absorption and enhance its elimination. Hypokalemia is a potential adverse effect of this drug; conversely, in patients with concomitant hyponatremia, the sodium load from Kayexalate can be beneficial.
Enhanced elimination
Volume resuscitation with normal saline or one-half isotonic sodium chloride solution may be effective in enhancing renal elimination of lithium in individuals with mild-to-moderate toxicity. Avoid onset of hypernatremia.
Hemodialysis has been the mainstay of therapy in severe lithium intoxication, although the specific indications are poorly established.

[ArchivalUser]

Preliminary studies in animals and humans suggest that sodium polystyrene sulfonate (Kayexalate) is capable of binding lithium and may prevent lithium absorption and enhance its elimination. Hypokalemia is a potential adverse effect of this drug; conversely, in patients with concomitant hyponatremia, the sodium load from Kayexalate can be beneficial.
Enhanced elimination
Volume resuscitation with normal saline or one-half isotonic sodium chloride solution may be effective in enhancing renal elimination of lithium in individuals with mild-to-moderate toxicity. Avoid onset of hypernatremia.
Hemodialysis has been the mainstay of therapy in severe lithium intoxication, although the specific indications are poorly established.

[ArchivalUser]

THANK

[ArchivalUser]

any patient with change in mental status becouse of lithium toxicity has to be considered for hemodyalisis....tht is something to be always remembered when we are facing patients tht take lithium