Thalassemia-Goljan-errata? - paganini

[ArchivalUser]

The book says Mild anemia (B-Thal) is most often due to DNA splicing defects.
I think it should be RNA splicing defect. Splicing occurs in mRNA not in DNA.
Can anyone correct me?

[ArchivalUser]

DNA defects-mutations leading to new splice sites on the DNA cousing abnormal mRNA splicing.

[ArchivalUser]

But splice sites are on primary mRNA or not?

[ArchivalUser]

yes of course they are on mRNA