nbme 1 q 31 - biochem510

[ArchivalUser]

a 4 yr old girl is brought to the ER bc of 5 day history of fever, diffuse abd pain, nausea, vomiting, and diarrhea. examination shows petechiae,hepatomegaly,splenomegaly. Hb conc is 8.7 and platelet cound is 60,000. PBF shows erythrocyte fragmentation. which of the foll renal findings is most likely ass with her condition?

Glomerular crescent formation
IgG ass glomerular basment membrane Ab
membranoprolif GN
narrowing of the capillary wall by fibrin deposition
periglomerular granuloma with giant cells

[ArchivalUser]

narrowing by fibrin depo

[ArchivalUser]

could u please explain this thanksss

[ArchivalUser]

this is a case of HUS....normally u would expect widespread fibrin deposition in small caliber vessels....leading to microangipathic hemolytic anaemia...

[ArchivalUser]

thanks "darkhorse"

[ArchivalUser]

narrowing of the capillary wall by fibrin deposition....