02-09-2007, 10:56 AM
8. A 70-year-old woman has increasing weakness, weight loss, generalized lymph node enlargement, and hepatosplenomegaly. Laboratory studies show absolute lymphocytosis with the majority of cells being CD5+. The patient also has a mild antiglobulin-positive hemolytic anemia. Karyotype is normal. Which of the following is the most likely diagnosis?
A ) Acute lymphoblastic leukemia
B ) Acute promyelocytic leukemia
C ) Chronic lymphocytic leukemia
D ) Chronic myeloid leukemia
E ) Fanconi's anemia
F ) Hairy cell leukemia
G ) Myelodysplastic syndrome
H ) Myeloid metaplasia with myelofibrosis
A ) Acute lymphoblastic leukemia
B ) Acute promyelocytic leukemia
C ) Chronic lymphocytic leukemia
D ) Chronic myeloid leukemia
E ) Fanconi's anemia
F ) Hairy cell leukemia
G ) Myelodysplastic syndrome
H ) Myeloid metaplasia with myelofibrosis