02-22-2007, 07:00 PM
what type of fatty change occurs in reye's syndrome and alcoholics??????????????????
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fatty change - drvirgo
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02-22-2007, 07:14 PM
alcholic-- microvesicular
rey syn---- microvesicular??????
02-23-2007, 06:17 AM
reyes--microvesicular
2-alcohol----macrovesicular
02-23-2007, 07:08 AM
Goljan says in his lecture that is crap to diferentiate micro/macro....usaually is a mixture of both...so is up to you guys!
02-23-2007, 09:21 AM
well if i remember it was about micronodular and macronodular cirrhosis.but no doubt micro/maro steatosis is a total crab
02-23-2007, 09:32 AM
OK ...sorry my bad...was too late last night !!!!
Here is the answer: Alcoholic fatty change represents the intracytoplasmic accumulation of triglyceride (neutral fats). At the beginning, the hepatocytes present small fat vacuoles (liposomes) around the nucleus - microvesicular fatty change. In the late stages, the size of the vacuoles increases pushing the nucleus to the periphery of the cell - macrovesicular fatty change. Microvesicular steatosis is typical of Reye's syndrome, problem pregnancies, mitochondrial problems, and toxicity from outdated-tetracycline poisoning. hOPE YOU will forgive me for my mistake. thanks! |
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