03-25-2007, 02:59 PM
You are evaluating an 8-year-old child with abdominal pain for possible appendicitis. Laboratory testing shows a white blood cell (WBC) count of 7.9 x 109/L. You are wondering whether to pursue the diagnosis further, when your attending physician remarks that the absence of leukocytosis has a negative predictive value (NPV) of 62% for appendicitis. Based on this information, what would you conclude?
A. The probability of not having appendicitis is 62% in the absence of leukocytosis
B. Approximately 62% of patients without appendicitis will not have leukocytosis
C. The positive predictive value for leukocytosis is 38%
D. You need to review your evidence-based medicine
A. The probability of not having appendicitis is 62% in the absence of leukocytosis
B. Approximately 62% of patients without appendicitis will not have leukocytosis
C. The positive predictive value for leukocytosis is 38%
D. You need to review your evidence-based medicine