fludrocortisone therapy-nbme1 - parmida

[ArchivalUser]

A 72-year-old man comes to the physician because of an 8-month history of feeling light-headed when he stands up. Blood pressure is 130/85 mm Hg while supine and 94/64 mm Hg while standing. High-dose fludrocortisone therapy is started. After 5 days of treatment, laboratory studies are most likely to show which of the following changes?

Serum K+; Renin; Urine K+ excretion

A ) ↓ ↑ ↑

B ) ↓ ↑ ↓

C ) ↓ ↓ ↑

D ) ↑ ↑ ↓

E ) ↑ ↓ ↑

F ) ↑ ↓ ↓

[ArchivalUser]

hypokalaemic alkalosis with hypocalcaemia ..and HTN N oedema
ans =C

[ArchivalUser]

Most adverse reactions are caused by the drug's mineralocorticoid activity (retention of sodium and water) and include hypertension, edema, cardiac enlargement, congestive heart failure, potassium loss, and hypokalemic alkalosis.