08-24-2007, 06:43 AM
how`d one differentiate old infection from vaccination serologically?
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hep.B.. - bergkamp
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08-24-2007, 06:45 AM
hbsag beyond six months indicatse chonic infection.
08-24-2007, 06:50 AM
i mean..if the patient can`t recollect or whatever..and denies any previous hep B
08-24-2007, 06:53 AM
then igg to core antigen?i dnt remember exactly.but u look for igg
08-24-2007, 07:03 AM
antihbsag is seen in vaccinated persons whereas both anti bvc and anti hbsag are found in old infections...just realised today that hbsag is used in the vaccine so it`s easy to remember that way...thought i`d share this here if it can help anyone
08-24-2007, 07:08 AM
hey take care anti hbsag provides protection against hep b so in chronic carrier state the matter is i think lil bit different too.yes u r right but old infection and chronic carrier are different things.old infection may mean recovered from hepb.
08-24-2007, 07:37 AM
hey guys my 2 cents ,
In chronic infection -HBsAg +,antibodies to core antigen will be positive but IgG,HBeAg may or may not be +,BUT there will not be any protective antibodies means antibodies to surface antigen negative. In old or prior infection -antibodies to both HBcAg (IgG) and HBsAg will be present. In vaccinated persons only antibodies to surface antigen will be present. |
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