09-15-2007, 11:15 AM
A 46-year-old woman presents with insidious onset of shortness of breath, chest pain, and fatigue. Chest
x-ray films reveal bilateral pulmonary infiltrates and enlarged hilar lymph nodes. A biopsy of
one of these lesions shows non-necrotizing granulomas. Special stains for fungi and
mycobacteria are negative. The patient works as a secretary and has no history of occupational
exposure to airborne minerals or organic dusts. Which of the following is the most likely
diagnosis?
A. Asbestosis
B. Berylliosis
C. Byssinosis
D. Sarcoidosis
E. Tuberculosis
x-ray films reveal bilateral pulmonary infiltrates and enlarged hilar lymph nodes. A biopsy of
one of these lesions shows non-necrotizing granulomas. Special stains for fungi and
mycobacteria are negative. The patient works as a secretary and has no history of occupational
exposure to airborne minerals or organic dusts. Which of the following is the most likely
diagnosis?
A. Asbestosis
B. Berylliosis
C. Byssinosis
D. Sarcoidosis
E. Tuberculosis