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what is the d/f? - epos
#1
What is the d/f b/n ALS,GBS and poliomyelitis?
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#2
Amyotrophic lateral Sclerosis(Lou Gehring's Disease) Degenerative motor neurone disease , both UMN and LMN signs with no sensory loss.

Quote:In ALS, both the upper motor neurons and the lower motor neurons degenerate or die, ceasing to send messages to muscles. Unable to function, the muscles gradually weaken, waste away, and twitch. Eventually the ability of the brain to start and control voluntary movement is lost. Individuals with ALS lose their strength and the ability to move their arms, legs, and body. When muscles in the diaphragm and chest wall fail, individuals lose the ability to breathe without ventilatory support. The disease does not affect a person's ability to see, smell, taste, hear, or recognize touch, and it does not usually impair a person™s thinking or other cognitive abilities. However, several recent studies suggest that a small percentage of patients may experience problems with memory or decision-making, and there is growing evidence that some may even develop a form of dementia. The cause of ALS is not known, and scientists do not yet know why ALS strikes some people and not others.
http://www.ninds.nih.gov/disorders/amyot...erosis.htm


Guillain Barre Syndrome -ass with infection, stress, innoculations causing inflammation and demyelination of peripheral nerves and motor fibres of ventral roots >>>Sensory affected less than motor.
symetrical ascending muscle weakness beginning from lower extremities. Autonomic function maybe affected . Patients almost all survive, recover fully after weeks or months.

Thats why its also known as Acute Idiopathic polyneuritis.


and


poliomyelitis follows an infection(poliovirus - fecal-oral) LMN signs degeneration of anterior horns.
LMN: muscle weakness and atrophy, fasciculations, fibrillation and hyporeflexia.
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