03-21-2008, 09:41 AM
it gives but it states that she taked alcholo occasionally
try this - zkadhem
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03-21-2008, 09:41 AM
it gives but it states that she taked alcholo occasionally
03-21-2008, 09:42 AM
bb
03-21-2008, 09:44 AM
15. The correct answer is B. An isolated GGT elevation
may be the only laboratory abnormality seen in a clinically stable alcoholic patient. Although the test is by no means sensitive enough to use for screening purposes, an isolated GGT level (relative to alkaline phosphatase and other liver function tests) should raise the possibility of alcohol abuse. This patient was recently fired from work (raising the question why), reports depressive symptoms, and has rhinophyma, a physical finding loosely associated with alcohol use. Other drugs that can cause an isolated GGT elevation include barbiturates and phenytoin. Acetaminophen (choice A) toxicity will present with massive transaminitis, with levels in the thousands. An isolated GGT elevation, which can indicate early liver disease, is not consistent with acetaminophen toxicity. In many patients, amiodarone (choice C) can cause a moderate increase in serum transaminases and, rarely, more severe hepatic injury. Hepatomegaly is usually present, and a transaminitis, not an elevation of cholestatic markers such as GGT, is more likely. Atorvastatin (choice D), like all statins, can cause elevations of liver enzymes, though they often return to normal. Again, the pattern is a transaminitis, not an isolated elevation of GGT. Metformin (choice E), which acts primarily by limiting hepatic gluconeogenesis, needs to be used cautiously in patients with liver failure. It is not, however, commonly associated with hepatic abnormalities. |
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