05-23-2008, 09:11 AM
Ms. Andrews, a 30-year-old female, was admitted because of community acquired pneumonia last night and was on Zithromax (Azithromycin). You find the lady in an altered mental status with fluctuating neurological signs. Her vitalis are, Temperature: 37.9C(100.3F); BP: 108/72 mm Hg; PR: 87/min; RR: 21/min. There are marked pallor and petechial rash present on examination. The labs are:
Sodium 136 mEq/L
Potassium 3.7 mEq/L
Bicarbonate 29mEq/L
Blood urea nitrogen 24mg/dL
Creatinine 1.6 mg/dL
Glucose 82 mg/dL
WBC 8,600mm3
Hemoglobin 8.9
Hematocrit 31%,
Platelets 34,000mm3
Bleeding Time 6 min
PT 12.1s
APTT 30s
Peripheral smear shows severely fragmented red blood cells. What is the most probable diagnosis?
A. Idiopathic thrombocytopenic purpura
B. Disseminated intravascular coagulation
C. Hemolytic uremic syndrome
D. Thrombotic thrombocytopenic purpura
E. Glazmannā¢s thrombasthenia
Sodium 136 mEq/L
Potassium 3.7 mEq/L
Bicarbonate 29mEq/L
Blood urea nitrogen 24mg/dL
Creatinine 1.6 mg/dL
Glucose 82 mg/dL
WBC 8,600mm3
Hemoglobin 8.9
Hematocrit 31%,
Platelets 34,000mm3
Bleeding Time 6 min
PT 12.1s
APTT 30s
Peripheral smear shows severely fragmented red blood cells. What is the most probable diagnosis?
A. Idiopathic thrombocytopenic purpura
B. Disseminated intravascular coagulation
C. Hemolytic uremic syndrome
D. Thrombotic thrombocytopenic purpura
E. Glazmannā¢s thrombasthenia