PTH and Calcium levels in renal disease - guest1

[ArchivalUser]

can someone please help me with this question, as how it changes. Also, how it is in paraneoplasic disease. I always mess this up. So, I'd really appreciate your help in this.


Thank you.

[ArchivalUser]

Paraneoplastics usually increase PTH and secondary Ca
Renal failure usually saves P, which means lower bld Ca and increase PTH. Reanl problem also messes up Vit D, which leads to decreased P and Ca absorbtion which lower both of them down and increases PTH
Am I right?

[ArchivalUser]

In renal failure:

↑P b/c kidney malfunction, ↓Ca b/c P is high, ↑PTH b/c Ca is low


In paraneoplastic sydrome, it is more complicated: ↑Ca, ↓PTH

Hypercalcemia due to secretion of PTH-like peptide.

PTH-like peptide increases the renal reabsorption of calcium and decreases P reabsorption.

The hypercalcemia lowers the patient's own PTH.

Please correct me if wrong

thanks

[ArchivalUser]

i think thats perfect

[ArchivalUser]

thanx a lot guys..... this helps a lots...thanx for clearing for me..... thanx erg, okt3, zuzu.