Conceptual Q ------------------------------ gene - irfanmir

[ArchivalUser]

oncogenes occurs at each stage of cell cycle including growth factor

example: platelet derived growth factor-----sis oncogene-----astrocytoma, osteorarcoma

[ArchivalUser]

example: platelet derived growth factor-----sis oncogene-----astrocytoma, osteosarcoma

[ArchivalUser]

I remember PDGF receptor , for example if mutated, can function as oncogene, but not PDGF itself. May be i am wrong.

[ArchivalUser]

please explain irfanmir

[ArchivalUser]

Oncogenes are genes involved in growth promotion. Growth factors, their receptors, signal transduction pathways, and transcription factors are all part of this process. DNA mismatch repair genes assist in DNA replication.

sorry guys im working cant ans right away. see u

[ArchivalUser]

http://www.med.umich.edu/lrc/coursepages...allqs.html