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hypernatremia - zesty
#1
83-year-old woman is admitted to a nursing home for ongoing management of Parkinson disease. Her husband can no longer care for her at home because she is moderately demented, has difficulty walking, has fallen several times and has urinary incontinence. She has difficulty swallowing her pills, and she needs assistance with feeding. Despite her husband's attentive care, she has lost 9 kg (20 lb), going from 47.1 kg (104 lb) to 38 kg (84 lb) during the past 9 months. After 2 weeks in the nursing home, the nursing staff notes that the patient frequently eats and drinks very little and often coughs after she swallows. Her current medications include fluoxetine, selegiline, carbidopa-levodopa, trazodone, estrogen and sorbitol. Vital signs now are: temperature 36.4°C (97.6°F), axillary; pulse 88/min; respirations 18/min and blood pressure 102/84 mm Hg, supine. Physical examination shows a frail and thin woman. Voice is soft and low. Chest is clear to auscultation. Heart rate is regular without murmurs or gallops. Abdomen is soft and nontender with decreased bowel sounds. Rectal examination is normal. She is generally stiff with low amplitude tremors at rest. Laboratory results show:

Serum
BUN47 mg/dL
Creatinine1.9 mg/dL
Na+161 mEq/L
K+3.9 mEq/L
Cl-120 mEq/L
HCO3-24 mEq/L

When the nursing home calls you with the laboratory results, the office staff informs you that the patient's husband telephoned earlier that afternoon and "fired" you from the case. There are no written notes from the staff and you have not spoken to the husband yourself.
23. Which of the following complications is most likely to develop if her hypernatremia is corrected too quickly?

A) Disseminated intravascular coagulation
B) Intravascular hemolysis
C) Pontine myelinolysis
D) Pulmonary edema
E) Seizures

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#2
C) Pontine myelinolysis
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#3
too rapid correction=> cerebral edema => SEIZURE is the answer!
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#4
yeah
u r correct high
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#5
HIGH!!
pontine myelinosis is a definite complication
but what occurs first
siezure of pontine mylinosis
or siezure is a complication of pontine mylinosis
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#6
seizure .....pontine myelinosis occurs after rx of hypo natremia not in hypernatremia...plus in hypernatremia rapid treatment leads to cerebral edema......
pontine myelinosis leads to dysarthria,paraplegia and other neuro problems but seizure is indicating cerebral edema
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#7
eeeeeee
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#8



EEE

ZESTY Pontine myelinosis a by hypOnatremia....... Does it happer with haper?????



The cornerstone of treatment is administration of free water to correct the relative water deficit. Water can be replaced orally or intravenously. However, overly rapid correction of hypernatremia is potentially very dangerous. The body (in particular the brain) adapts to the higher sodium concentration. Rapidly lowering the sodium concentration with free water, once this adaptation has occurred, causes water to flow into brain cells and causes them to swell. This can lead to

cerebral edema, potentially resulting in seizures, permanent brain damage, or death.

Therefore, fast correction causes more problem that hypernatremia itself


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#9
Agree- in short::

Overcorrection of Hypernatremia--cerebral edema- seizures. Rx- fluids
Overcorrection of HyPOnatremia--central POntine myelinosis. Rx restric fluids/hypertonic saline--very slow incre in Na levels.
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