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pancreatic insufficiency - han80
#1
most specific n sensitive test?
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#2
no one?its stool elastase
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#3
good job han80?
How about test for fat malabsorption?
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#4
Tests of fat malabsorption

This usually is the first test because many disease processes result in fat malabsorption.
For a quantitative measurement of fat absorption, a 72-hour fecal fat collection is often performed and is considered the criterion standard.

D-xylose test

If the 72-hour fecal fat collection results demonstrate fat malabsorption, the D-xylose test is used to document the integrity of the intestinal mucosa.
Facilitated diffusion in the proximal intestine primarily absorbs D-xylose.
Approximately half of the absorbed D-xylose is excreted in urine, unmetabolized. If the absorption of D-xylose is impaired due to either a luminal factor (eg, bacterial overgrowth) or a reduced or damaged mucosal surface area (eg, surgical resection, celiac disease), urinary excretion is lower than normal.
Cases of pancreatic insufficiency usually result in normal urinary excretion because the absorption of D-xylose is still intact.
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