NBME form 5 q GIT - sarah00

[ArchivalUser]

67y/o woman with pernicious anemia has absent gastric parietal cells .Inc in which is most likely additional finding

a gastrin in blood
b protein digestion in stomach
c secretin in blood
d secretion of gastric acid
e secretion of intrisic factor

[ArchivalUser]

i think its aaa. Since parietal cells are missing, acidity will decrease causing an increase in gastrin...

[ArchivalUser]

yep
also less acidity ---> decrease pepsin activation ---> DECREASE protein digestion in stomach
also less acidity ---> decrease secretin release (secretin's function is to neutralize the stomach acidity that reaches the duodenum