" a 35 yrs old pt c a rash on her face" - tibebe

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of 2 mths duration. the rash involves both of the maxilary areas and the bridge of her nose that is exacerbated c sun exposure ,has bilateral symmetrcial joint pain in both her hands, c a low grade fever. and recently complained of muscle weakness in her proximal legs & arms and started to experience some difficulty while walking long distances & combing her hair .since the last 3 wks she noticed her skin on the dorsum of her hands to become very thick .the physician after evaluating the pt ,wants to confirm his dx and ordered an investigaton. w/c of the ff is the most likely one?
a.anti centromere
b.anti ds-DNA
c. anti -Sm
d.anti- jo-1
e.ribonucleic protein antibody
f.HLA-B27

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ee

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e.

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mctd rbnp ab

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e.
mixed connective tissue disease.

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ee