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IL1or IL6 OSTEOCLAST ACTIVATING FACTOR - laiba07

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IL1or IL6 OSTEOCLAST ACTIVATING FACTOR - laiba07
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#1
02-06-2009, 07:15 PM
GOLJAN said it,s il1 kaplan says it,s il6
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#2
02-06-2009, 07:52 PM
il 1...
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#3
02-06-2009, 08:10 PM
usmleworld wich is very update said that it is IL 1.
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#4
02-06-2009, 08:16 PM
IL-6 in MM
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#5
02-07-2009, 12:23 AM
Both r osteoclast activating factor
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#6
02-07-2009, 08:00 AM
This is new, so both Il1 and IL 6 are OAF ??
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#7
02-07-2009, 08:15 AM
Both Osteoclast activating property but the source, mechanism and purpose are different.
IL1 is classic (estrogen inhibits) Source is Osteoblasts, PTH mediates IL1 stimulation to release Ca2+
In MM, the cause of multiple lytic lesions is IL6 mediated osteoclast activation. The source is malignant plasma cells.
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#8
02-07-2009, 08:23 AM
Estrogen inhibit both 1 & 6
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#9
02-07-2009, 08:24 AM
Estrogen inhibit both 1 & 6
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