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nephrologyq 32 - tacrolimus99
#1
An 80-year-old man is evaluated for a routine examination. He has a history of hypertension and was diagnosed with chronic osteoarthritis 20 years ago. Medications are atenolol, 50 mg/d, and hydrochlorothiazide, 25 mg/d. One year ago, he began ibuprofen, 250 mg four times daily.

On physical examination, pulse rate is 60/min and blood pressure is 180/90 mm Hg without orthostatic changes. There is trace peripheral edema.

Laboratory Studies
Blood urea nitrogen 40 mg/dL
Creatinine 1.5 mg/dL
Sodium 134 meq/L
Potassium 4.9 meq/L

Which of the following treatment strategies is indicated for this patient?
a.ncrease the atenolol dose
b. Increase the hydrochlorothiazide dose
c.Add lisinopril
d.Discontinue ibuprofen
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#2
CCCCCC?
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#3
DDDD
Nonsteroidal anti-inflammatory drug use is a common cause of resistance to antihypertensive therapy. NSAIDS cuase decrease na excretion
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