05-12-2009, 03:36 PM
Biopsy of a reasonably well-demarcated mass of the nasopharynx demonstrates a plasma cell proliferation.
Serum electrophoresis shows a small monoclonal IgG spike. Bone marrow evaluation fails to
demonstrate plasma cell proliferation and no lesions are seen on extensive skeletal x-rays.
Which of the following is the most likely diagnosis?
A. Heavy chain disease
B. Monoclonal gammopathy of undetermined significance
C. Multiple myeloma
D. Plasmacytoma
E. Waldenström's macroglobulinemia
Serum electrophoresis shows a small monoclonal IgG spike. Bone marrow evaluation fails to
demonstrate plasma cell proliferation and no lesions are seen on extensive skeletal x-rays.
Which of the following is the most likely diagnosis?
A. Heavy chain disease
B. Monoclonal gammopathy of undetermined significance
C. Multiple myeloma
D. Plasmacytoma
E. Waldenström's macroglobulinemia