Q5-retinoblastoma too - purplepen

[ArchivalUser]

During a well child examination of a 3 year old boy, a pediatrician notes that he cannot see a normal red light reflex in the child's left eye. Further evaluation by a pediatric ophthalmologist reveals a retinal mass, which on surgical removal, proved to be a retinoblastom. Children who are predisposed for this tumor by a germline mutation are aslo predisposed for which of the following?
A. Acoustic neuroma
B. Colon cancer
C. Neurofibroma
D. Osteosarcoma
E. Wilms tumor

[ArchivalUser]

C.....Rb

[ArchivalUser]

e - wilms tumor

[ArchivalUser]

bipolar you are wrong,Rb is TSG associated with retinoblastoma and Osteogenic sarcoma.

[ArchivalUser]

check FA page 233,2004 edition.

[ArchivalUser]

i agree with lsa...most common second malignancies which occur in later life of children with retinoblastoma are....osteogenic sarcoma, lung and breast cancer.
neha.

[ArchivalUser]

thank u lsa
i read that it is related with osteosarcoma both are in chromosome 13q14 Gene RB

[ArchivalUser]

D.osteosarcoma

[ArchivalUser]

Isa is right.

D. Osteosarcoma.