carcinoid - yazdoc

[ArchivalUser]

everywhere it is given appendix is most common site for carcinoid.
uw says ileum

pls clarify

[ArchivalUser]

ya appendix is the most co site but when it comes to carcinoid tumors leading to carcinoid syndrome ileum is the most common cause

[ArchivalUser]

got it

[ArchivalUser]

I remember this Q. I made the same mistake. But I was thinking even worst by selecting lung cancer as my ans..

I knew like everybody that appendix is the MC site overall. But the patient was symptomatic in this Q, and somehow I couldn't get rid of the thought that lung carcinoma are more likely to be symptomatic (better prognosis), as serotonin produced by lung by passes liver and don't get metabolize.

Where as for intestinal carcinoids to become symptomatic they must wear out the capacity of liver to metabolize Serotonin. This could take time, but by the time it shows its symptoms it's already metastasized ( bad Q )

Do you think my read on this Q is legit or is there any better explanation to this Q?

[ArchivalUser]

most common site of carcinoid = tip of appendix that is NOT CARCINOID SYNDROME

Carcinoid syndrome (diarrhea --> flushing) (or as i like to say..."everything comes out")

is ONLY when it metastasizes....how?


TERMINAL ILLEUM ----> LIVER with invasion and metastasis


they can be in the

foregut (stomach)

Midgut (Terminal Illeum)

[ArchivalUser]

hindgut (rectum)


****REMEMBER******

its the size that matters-----bigger = worse

its obvious that if its gonna show up symptomatic....its pretty big.....