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How erythromycin can cause .... - zkadhem
#1
syncope, or even sudden death? Wink)
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#2
lol so why no one wants to reply? I was reading a case about it ! May be not step 3 question but u never know, may be u will have a wiered question like this!!!!

It causes prolongation of the QT interval which may lead to more malignant ventricular arrythmia torsades de pointes and VF!!!!


Please, try to correlate clinical information with possible cases and subsequently possible mcq!
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#3
zkadhem thanx! nice q Smile...Wink!? causes arrytmia too!!!gosh wht a medicine!
i got a q about erythro==> causes pyloric stenosis!!
Infantile hypertrophic pyloric stenosis after pertussis prophylaxis with erythromycin
dats a wird drug!!!
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#4
causes pyloric stenosis?

erythromycin also increases GI peristalisis..
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#5
erythromycin causes arrhythmias when combined with enzyme inducers like ketoconazole, cimetidine etc. in such cases other macrolides like roxithromycin or azithromycin can be used. i think even clarithro has similar adv effect like erythro
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#6
what other side effects for this family?
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#7
arrythmias are qt prolongation torsadepointes
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#8
This is a concept I learned in step-1 and this is how I remember Torsade de pointes causing drugs:

Quinidine Produces Extremely Bad Tachy Cardias
Quinidine Procainamide Erythromycin Bepridil Thioridazine Cisapride
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